New Generation GcMAF – Discover the effects
Proved by numerous clinical trials!
Approved as food/supplement in various countries and patented worldwide.
GcMAF has proved its effects in the medical fields around the world. GcMAF is acknowledged for its function to help the recovery from serious illness such as cancer and autism, and recently found in clinical trials in Ukraine, to have positive effects on patients with Covid-19.
Saisei Australia, a branch of Japan-based Saisei Pharma, was established in Sydney in 2019 and is now located on the Gold Coast. To meet growing demand in Australia and New Zealand, we expanded operations for easier access to our products. From the Gold Coast, we proudly ship our MAF series whey-based food products, registered as Food Products in Japan. Saisei Pharma holds the worldwide patents for its products, ensuring quality and innovation.
Anti-aging and longevity
Experience the groundbreaking innovation in anti-aging science with Dietary MAF—the only clinically proven solution to extend telomeres by an extraordinary 23% within just six months. Carefully developed by Saisei Pharma, these products are designed not only to enhance your health and appearance but to help you achieve the remarkable goals of looking 20 years younger and living vibrantly well past a century.
Aging is a natural part of life, yet our understanding of it has advanced significantly. Today, there are effective ways to slow this process. Central to these developments are macrophages, vital cells that play a key role in strengthening the immune system and eliminating damaged or unhealthy cells. These remarkable cells contribute to essential functions such as tissue repair, rejuvenation, and regeneration. They also provide robust protection against infections and unchecked tumor growth.
Dietary MAF harnesses cutting-edge science to challenge the inevitability of aging, fostering a life filled with vitality and resilience. Its efficacy is underscored by detailed analyses, including studies on the impact of MAF capsules on telomere length, which have demonstrated remarkable outcomes.
Analysis of the effect of taking MAF capsules on telomere length changes
nutrients
frontiers
Springer Nature
ScienceDirect
Scientific Reports
Dietary MAF Series
Dietary MAF (Macrophage Activating Factor) Series boosts immunity by activating the immune cells without any side effects. Stay young and healthy by taking these anti-aging supplements.
Free from
Wheat, soy, egg, rice, gluten, starch, sugar*, hormones, antibiotics, preservatives, artificial sweeteners, artificial colors.
*Sugar is contained in M-Lollies
Topical and Oral
MAF is available in both topical and oral supplement forms. The 4 types of MAF products allows MAF to be absorbed from the mouth, intestines and the skin. The MAF Series is made exclusively with natural ingredients.
Uniqueness
MAF was developed using our own unique patented method. MAF helps boost the immune system by activating macrophages without any side effects.
Factory in Japan
MAF Series is produced in our Saisei Mirai GMP factory in Moriguchi, Osaka. The factory is certified by the Ministry of Health, Labor and Welfare of Japan.
Advancements in GcMAF: Unveiling Enhanced Rejuvenation Effects
First-generation GcMAF. While it activated macrophages, it did not induce rejuvenation.
Second-generation GcMAF. Some rejuvenation effects were observed.
Deitary MAF while it still activates macrophages, its rejuvenation effects are particularly strong. In mouse studies, MAF has shown telomere elongation and increased expression of telomerase (TERT and TERC), making the subjects resemble their younger state. Additionally, the expression of the Klotho gene was also enhanced.
Therefore, we believe that MAF induces rejuvenation through mechanisms beyond macrophage activation—primarily through its effects on telomeres, telomerase (TERT and TERC), and the Klotho gene. We hypothesize that TERT and TERC activation leads to telomere elongation, contributing to longevity.
Manufactured in Japan with global patents
Unlocking the Secrets of Telomeres & Aging
Ever wondered why we age? The answer lies in telomeres —the protective caps at the ends of our chromosomes.
Degalactosylated Whey Protein (D-WP) Study – Effects on Telomere Length in Mice
A separate experimental study examined the effects of D-WP on telomere length and telomerase gene expression in young and aged mice.
📌 Findings:
✔ D-WP increased telomere length by 154% in young mice, while regular whey protein (WP) showed only a 121% increase.
✔ D-WP significantly upregulated telomerase reverse transcriptase (TERT) and telomerase RNA component (TERC) gene expression in peripheral blood.
✔ In aged mice, D-WP restored telomere length to youthful levels.
📌 Implication: D-WP, a key component in MAF Triple, enhances telomere maintenance, supporting longevity and cellular health.
🔗 Access the full study: Scientific Reports (2024)
Phase 2 Clinical Trial in Japan
📌 Study Objective: Evaluating the efficacy of Dietary MAF for rejuvenation and longevity
📌Number of Participants: 161
📌Results: ✔ Telomere length increased by 12% at 3 months
✔ Telomere length increased by 23% at 6 months
✔ Biological age reduction observed within 6 months of MAF Triple intake
🔬 Ongoing Research: A similar clinical trial is currently being conducted in Indonesia to further evaluate MAF Triple’s rejuvenation and longevity effects.
Association with Aging
Link to Age-Related Diseases
Shortened telomeres have been associated with age-related conditions such as...
Read MoreBoost your immunity with MAF Series
MAF = Macrophage Activating Factor
Our Dietary MAF boosts your immunity by activating the immune cells without any side effects and help you stay young and healthy. The MAF Series is made exclusively with natural ingredients and produced in Osaka, Japan.
How MAF Triple Enhances Macrophage Activation for Optimal Immune Defense
Your immune system relies on macrophages—specialized cells that identify and eliminate harmful pathogens. However, due to aging, stress, or environmental factors, macrophages can become sluggish and ineffective. By promoting this natural immune cycle, MAF Triple supports overall health, resilience, and rapid immune response.
MAF Triple (Macrophage Activating Factor) helps revitalize your immune function by guiding macrophages through three crucial activation stages:
Aged, Stressed State:
Inactive macrophages fail to respond to infections.
Primed State:
Macrophages start preparing to combat pathogens without producing inflammatory cytokines.
Triggered State:
Fully activated macrophages effectively fight infections by engulfing pathogens and releasing immune-boosting cytokines.
Resident macrophages are present throughout the human body,
from the brain (microglia) and eyes (intraocular macrophages) to the lungs (alveolar macrophages), liver (Kupffer cells), spleen (splenic macrophages), intestines (intestinal macrophages), bone marrow, lymph nodes, skin (Langerhans cells), and even bones (osteoclasts), where they play essential roles in immune defense, antigen presentation, tissue homeostasis, and pathogen clearance.
What are macrophages?
from the brain (microglia) and eyes (intraocular macrophages) to the lungs (alveolar macrophages), liver (Kupffer cells), spleen (splenic macrophages), intestines (intestinal macrophages), bone marrow, lymph nodes, skin (Langerhans cells), and even bones (osteoclasts), where they play essential roles in immune defense, antigen presentation, tissue homeostasis, and pathogen clearance.